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rplR [2019-06-17 10:54:44]
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rplR [2019-06-17 10:54:44]

ribosomal protein
Locus
BSU01320
Isoelectric point
10.46
Molecular weight
12.88 kDa
Protein length
120 aa Sequence Blast
Gene length
363 bp Sequence Blast
Function
translation
Product
ribosomal protein L18
Essential
yes
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
142,974 → 143,336

Phenotypes of a mutant

  • essential PubMed
  • The protein

    Protein family

  • ribosomal protein L18P family (according to Swiss-Prot)
  • Structure

  • 1OVY (Geobacillus stearothermophilus)
  • 3J9W (the ribosome) PubMed
  • Expression and Regulation

    Operons

    Description

    Sigma factors

  • SigA: sigma factor, PubMed (two promoters, about 140bp and 200bp upstream of the start codon), in SigA regulon
  • Regulatory mechanism

  • stringent response: negative regulation, in stringent response
  • Regulation

  • strongly repressed in response to glucose starvation in M9 medium PubMed
  • likely autorepression of operon expression upon binding of excess of one ribosomal protein to the untranslated region of the mRNA PubMed
  • Additional information

  • term-seq has identified a potential novel regulatory RNA element (protein-dependent leader) including an intrinsic transcription terminator upstream of rpsJ PubMed
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    References

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